Peptide Database

Peptide NamePotential peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC166H266N58O64

DescriptionStandard

        NSSSGSAHQKREDVAAGEDRGLLPEGGPEPRGDGAGPGPRE
    

Molecular Weight4098.24 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-3.13

Net Charge (pH 7.4) -3.40

Charge Density (pH 7.0) -0.0764

GRAVY Index-1.36

Hydrophobic Moment 0.40

Boman Index-0.25

Instability Index41.74

Aliphatic Index 35.85

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1951.17

LogP -30.16

H-bond Donors 65.0

H-bond Acceptors 62.0

Rotatable Bonds 133.0

Heavy Atoms 288.0

Ring Count 6.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150556 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca nemestrina [Animal]

FamilyPotential peptide

Tax ID9545

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods1:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0150995 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0175954 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca nemestrina [Animal]

FamilyPOMC

Tax ID9545

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor