Peptide Database

Peptide NameMu/omega-theraphotoxin-Hs1a

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Venom / Toxin ▸ General toxin ▸ huwentoxin-1 family

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC161H252N48O44S6

DescriptionStandard

        ACKGVFDACTPGKNECCPNRVCSDKHKWCKWKL
    

Molecular Weight3756.41 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.82

Net Charge (pH 7.4) 3.48

Charge Density (pH 7.0) 0.1158

GRAVY Index-0.68

Hydrophobic Moment 0.46

Boman Index-0.18

Instability Index65.98

Aliphatic Index 35.45

Aromaticity 0.0909

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1493.76

LogP -15.20

H-bond Donors 57.0

H-bond Acceptors 55.0

Rotatable Bonds 122.0

Heavy Atoms 259.0

Ring Count 8.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0103579 VERIFIED: YES

Provenance & Taxonomy

OrganismHaplopelma schmidti [Animal]

Familyhuwentoxin-1 family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-17; 9-22; 16-29

Bio-Activity Profile

Function

Toxin Venom huwentoxin-1 family Ion channel inhibitor Pathogenesis-associated

RECORD: Rec_0190392 VERIFIED: NO

Provenance & Taxonomy

OrganismSelenocosmia huwena [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-17, 9-22, 16-29

Bio-Activity Profile

Function

Toxin