Peptide Database

Peptide NameColicin pyocin immunity family protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length868 amino acids

Chemical FormulaC4211H6769N1205O1252S23

DescriptionStandard

        MRNGNESSRSDSMTVSGSRPSGVHWGGGRGNNGGGDRHSSHKAVNKPKVDLLKTPEMQAYMAVGGMPAVITLIDNVWGITLTRHSVMSFLETNLSRVGAWAMRTSPIGVAVLGMMPSKIALDPPIGHYFTTPALPANRVTDTPKEALQVATDVAVNVRISDVTDAGVQHAVLHKTPVAIQRIPVVKAIATIRPNVFTVAVPGITPMHISVVDTIASENEAKLVAPTGKPTVTPIESTPVREFSLPEGRHTHDAIIVFPDSVDVEPIYLSVIRITSTHEIRQEAYNTYEIAKTEREVAERNRVQKKPFGSFIKEMTLQKTLTDSQVAETAAHIILLESKLTLLRQEEGQAWHQREYLIRIHGNKKFKYLHEVHGLRKLAQAKQGEIDVINQSIAKLKMEEMGLLIQQQRVNADLETAKITEPQRVENARLTAEAAEKAARDRRISEEIAATEAKRQRMENERLAEQERQRVEGTKQQVSEASCAQQASAWQNRFTLPALQPSGSAQYSFAASGMSAVALSPREAAKLHNSFLAAQEQLSAIATTSASGPVAAMIALEVYQTKVGESSERPPGWNVNPKFVGSISLSAMGLSATESLVSQGEMALPVRMRIIDAKDWIGCTEIYAVKTGVAGVLPKVKVGAAQYDESTGVYTFTTDSTPPRTLIFTPAQPPGAETRPILAPPGSAPATLQHTGEMIIKPVITPTILPLPQLYAHDFHDYIIWFPADSGLEPVYVYLKSPRDEPGVVTGRGERITGIWLVDAGKDMGAPIPAQIADKLRGRRFSNFGRFRAAFWKVVGEDPNLVKYFKSGNLGNIKNGKAPSPKEREQVGRRVKYELHHLKPISKNGAVYNIENIRVLTPKRHIDIHKGVE
    

Molecular Weight95046.61 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)14.71

Net Charge (pH 7.4) 13.03

Charge Density (pH 7.0) 0.0169

GRAVY Index-0.29

Hydrophobic Moment 0.63

Boman Index0.00

Instability Index44.28

Aliphatic Index 86.43

Aromaticity 0.0576

Extinction Coeff. Reduced 83310.00

Extinction Coeff. Oxidized 83435.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189453 VERIFIED: NO

Provenance & Taxonomy

OrganismYersinia similis [Bacterium]

FamilyColicin pyosin nuclease

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli