Peptide Database

Peptide NameDefensin-B2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC325H514N102O83S8

DescriptionStandard

        MEARVLLLCAVLFLLVHTPPAAGGLNNKCAYFRGQCRRKCPQRDIFFGFCRNHDQCCLSSLHTRH
    

Molecular Weight7434.71 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)5.78

Net Charge (pH 7.4) 5.25

Charge Density (pH 7.0) 0.0889

GRAVY Index-0.01

Hydrophobic Moment 0.48

Boman Index-0.03

Instability Index40.89

Aliphatic Index 81.08

Aromaticity 0.0923

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2971.00

LogP -28.63

H-bond Donors 111.0

H-bond Acceptors 101.0

Rotatable Bonds 241.0

Heavy Atoms 518.0

Ring Count 13.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301731 VERIFIED: NO

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence