Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC404H660N116O105S8

DescriptionStandard

        MKLLLLTLAVLLLLAQLTPGDAQRCWSSYGKCHRRCSPKDKVYVYCSNGKVCCVKPKYQVKERPWLISVPGTPMPGGNRRG
    

Molecular Weight9078.80 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1299

GRAVY Index-0.20

Hydrophobic Moment 0.58

Boman Index-0.04

Instability Index33.01

Aliphatic Index 86.54

Aromaticity 0.0741

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3539.72

LogP -31.28

H-bond Donors 130.0

H-bond Acceptors 125.0

Rotatable Bonds 295.0

Heavy Atoms 633.0

Ring Count 16.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079069 VERIFIED: NO

Provenance & Taxonomy

OrganismDipodomys ordii [Animal]

FamilyBeta-defensin; Defensin

Tax ID10020

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic