Peptide Database

Peptide Namegamma-gliadin 1375 (p61-p80; E62 and E65), ; gamma-gliadin M7 M36999 (61-80) homologous to DQ2-gamma-III

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC58H84N14O20

DescriptionStandard

        TEQPEQPFPQP
    

Molecular Weight1297.37 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.60

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.2360

GRAVY Index-1.98

Hydrophobic Moment 0.33

Boman Index-0.22

Instability Index182.47

Aliphatic Index 0.00

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 543.26

LogP -5.58

H-bond Donors 14.0

H-bond Acceptors 18.0

Rotatable Bonds 35.0

Heavy Atoms 92.0

Ring Count 5.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170762 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E62; Reported substitutions/positions: E65; Reported substitutions/positions: M7; Reported substitutions/positions: M36999

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay