Peptide Database

Peptide NameSLAY-screened peptide P371

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC96H147N25O33S

DescriptionStandard

        LSLHCDIGFNANNTLSTDYI
    

Molecular Weight2211.41 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-2.16

Net Charge (pH 7.4) -2.43

Charge Density (pH 7.0) -0.1081

GRAVY Index0.10

Hydrophobic Moment 0.34

Boman Index0.19

Instability Index14.88

Aliphatic Index 102.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 949.92

LogP -11.10

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 70.0

Heavy Atoms 155.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204620 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/