Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC450H735N121O138S2

DescriptionStandard

        SRIHVTAIELPSASISLLPGSGIKLVIGNASLTIDMNWSIRTWIFKDSGRGTVHISKVFVTAIFSTPLDNAGPTSIALTSCQTTSGDVDIKLNGKT
    

Molecular Weight10112.51 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)1.63

Net Charge (pH 7.4) 1.29

Charge Density (pH 7.0) 0.0170

GRAVY Index0.27

Hydrophobic Moment 0.54

Boman Index0.18

Instability Index15.02

Aliphatic Index 105.62

Aromaticity 0.0521

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4122.17

LogP -47.17

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 331.0

Heavy Atoms 711.0

Ring Count 13.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0119882 VERIFIED: NO

Provenance & Taxonomy

OrganismPrunella fulvescens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria