Peptide Database

Peptide NameDefensin; alpha; 42 (Defensin; alpha; 43)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length116 amino acids

Chemical FormulaC541H888N162O172S12

DescriptionStandard

        MKTLVLLSALALLALQVQADPIQNTDEETKTQEQPGEEDQAVSVSFGGTEGSALQDVAQRRFPWCRKCRVCQKCEVCQKCPVCPTCPQCPKQPLCKERQNKTAITTQAPNTHHKGC
    

Molecular Weight12798.60 Da

Isoelectric Point (pI)8.01

Net Charge (pH 7.0)1.58

Net Charge (pH 7.4) 1.08

Charge Density (pH 7.0) 0.0137

GRAVY Index-0.56

Hydrophobic Moment 0.53

Boman Index-0.13

Instability Index51.39

Aliphatic Index 64.74

Aromaticity 0.0259

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5410.89

LogP -65.67

H-bond Donors 189.0

H-bond Acceptors 188.0

Rotatable Bonds 426.0

Heavy Atoms 887.0

Ring Count 15.0

Amide Bonds 132.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0105777 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic