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MYP_065458
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Basic Information
hP3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
25 amino acids
C129H211N41O36
Standard
Sequence
TFRAFLSSRLQDLYSIVRRADRAAV
Physicochemical Analysis
2912.31 Da
11.42
2.40
2.21
0.0960
-0.01
0.82
-0.16
63.79
101.60
0.1200
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1290.06
-13.07
49.0
39.0
96.0
206.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008124 VERIFIED: YES
Provenance & Taxonomy
Human endostatin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 15867360 PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
RECORD: Rec_0038347 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0114613 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Endostatin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic Cytotoxic
BxPC-3
7 mg/kg/d
Inhibition
PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
RECORD: Rec_0289775 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
RECORD: Rec_0312500 VERIFIED: YES
Provenance & Taxonomy
Human endostatin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
BxPC-3 (No inhibition at 7 mg/kg/d)
PaperPubMed PMID: 15867360 PMID15867360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15867360/
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