Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC472H735N127O138S12

DescriptionStandard

        FPDGEFLMQGCPECKLGENRFFSKPGAPVYQCTGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKAFTKITLKDNVKIENHTECHCSTCYYHKS
    

Molecular Weight10781.43 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)4.93

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.0513

GRAVY Index-0.38

Hydrophobic Moment 0.64

Boman Index-0.04

Instability Index53.09

Aliphatic Index 49.79

Aromaticity 0.1042

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4239.54

LogP -45.17

H-bond Donors 155.0

H-bond Acceptors 158.0

Rotatable Bonds 349.0

Heavy Atoms 749.0

Ring Count 20.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155584 VERIFIED: YES

Provenance & Taxonomy

OrganismStruthio camelus [Animal]

FamilyGlycoprotein hormones

Tax ID8801

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min