Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H875N143O169S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISKIHVTAVEFPSASISLLPGTGIKLVIGNASLTIDMSWNIRTWMFKDSGRSTVYISKVSVTAIFSTPLDNTGHTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12242.84 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.04

Hydrophobic Moment 0.48

Boman Index0.13

Instability Index19.68

Aliphatic Index 93.16

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4998.36

LogP -57.20

H-bond Donors 180.0

H-bond Acceptors 177.0

Rotatable Bonds 405.0

Heavy Atoms 861.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046793 VERIFIED: NO

Provenance & Taxonomy

OrganismLophotis ruficrista [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria