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MYP_065330
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Basic Information
Hymenochirin-2B
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C138H232N34O36S
Standard
Sequence
LKIPGFVKDTLKKVAKGIFSAVAGAMTPS
Physicochemical Analysis
2975.59 Da
10.18
3.76
3.55
0.1295
0.47
0.71
0.22
-12.36
97.59
0.0690
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1108.86
-8.78
38.0
41.0
99.0
209.0
4.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094352 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
L. casei R0215 [
250 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0098105 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa MDR2 B31770 [
64 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0100774 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
S. pseudintermedium E140 [
64 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0102601 VERIFIED: YES
Provenance & Taxonomy
Congo dwarf clawed [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Gram-positive Staphylococcus aureus
20-40 μM
MIC
PaperThe hymenochirins: A family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae).
RECORD: Rec_0109359 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus MRSA B33424 [
32 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
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