Peptide Database

Peptide NameDEFA3 isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC445H706N124O131S8

DescriptionStandard

        MRTLAILAAILLVALQAQAEPLQARGDEVAAAPEEIPADNPEVVVSLAWDESLAPKDSGSRKNMACACRIPSCFAGERRYGTCFYLGRVWAFCC
    

Molecular Weight10145.64 Da

Isoelectric Point (pI)4.99

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0270

GRAVY Index0.20

Hydrophobic Moment 0.48

Boman Index0.10

Instability Index61.69

Aliphatic Index 90.53

Aromaticity 0.0745

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4041.62

LogP -37.97

H-bond Donors 145.0

H-bond Acceptors 137.0

Rotatable Bonds 324.0

Heavy Atoms 708.0

Ring Count 15.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0134237 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Bacterium]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence