Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1002H1569N287O300S9

DescriptionStandard

        METQRASLSLGRRLLWLLLLGLVLPSARAQAPSYREAVLRAVDQLNEKSSDANLYRLLELDPPPEQDAEDQGARKPVSFRVKETVCPRTSQQPVEQCDFRENGLVKQCVGTVTRYWIRGDFDITCNDLCWDGLVTLGSPLSPKGPWLAYLSVVWRFNHRLQTSYGRFRVWGYSAGCGTHSEESYQDQVLNSESPLECMRV
    

Molecular Weight22724.50 Da

Isoelectric Point (pI)6.16

Net Charge (pH 7.0)-1.36

Net Charge (pH 7.4) -1.82

Charge Density (pH 7.0) -0.0068

GRAVY Index-0.41

Hydrophobic Moment 0.67

Boman Index-0.07

Instability Index42.82

Aliphatic Index 83.30

Aromaticity 0.0900

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 43805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9483.55

LogP -119.36

H-bond Donors 338.0

H-bond Acceptors 310.0

Rotatable Bonds 718.0

Heavy Atoms 1598.0

Ring Count 38.0

Amide Bonds 217.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0231205 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCathelicidin

Tax ID9925

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal