Peptide Database

Peptide NamePGLR_SOLLC

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length457 amino acids

Chemical FormulaC2200H3473N603O692S19

DescriptionStandard

        EACSSRTPVQFVVPKNKNYLLKQITFSGPCRSSISVKIFGSLEASSKISDEALLYNYGSGNSEAYVSNVTVNEAKIIGAENGVRIKTWQGGSGQASNIKFLNVEMQDLTFWNCKNLKVNNLKSKNAQQIHIKFESCTNVVASNLMINASAKSPNTDGMVIQRNSILLLIIIFASSISTCRSNVIDDNLFKQVYDNILEQEFAHDFQATNFPCEGIIMENINLVGESGKPSEATCKNVHFNNAEHVTPHCTSLEISEDVHVSNTQYIQISDTIIGTGDDCISIVSGSQNVQATNITCGPGHGISIGSLVKYPIIIDQNYCDRVEPCIQQFSAVQVKNVVYENIKGTSATKVAIKFDCSYKDRRLWIAFDSVQNLVVGGGGTINGNGQVWWPSSCKINKSLPCRDAPTAYLSYLSKNIESNNNIDKVDKNGIKVINVLSFGAKGDGKTYDNIAFEQAWN
    

Molecular Weight50050.97 Da

Isoelectric Point (pI)6.44

Net Charge (pH 7.0)-1.67

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0036

GRAVY Index-0.19

Hydrophobic Moment 0.64

Boman Index0.05

Instability Index32.48

Aliphatic Index 88.27

Aromaticity 0.0788

Extinction Coeff. Reduced 52370.00

Extinction Coeff. Oxidized 53245.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245881 VERIFIED: YES

Provenance & Taxonomy

OrganismSolanum lycopersicum [Plant]; Lycopersicon esculentum [Plant]

Tax ID4081

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation reported

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme