Peptide Database

Peptide NameSLAY-screened peptide P2619

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length2 amino acids

Chemical FormulaC6H12N2O4

DescriptionStandard

SA

Molecular Weight176.17 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.2700

GRAVY Index0.50

Hydrophobic Moment 0.34

Boman Index0.22

Instability Index5.00

Aliphatic Index 50.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 112.65

LogP -2.10

H-bond Donors 4.0

H-bond Acceptors 4.0

Rotatable Bonds 4.0

Heavy Atoms 12.0

Ring Count 0.0

Amide Bonds 1.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379025 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/

RECORD: Rec_0388268 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCasein-derived peptide

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory

TargetDipeptidyl peptidase IV