Peptide Database

Peptide NameHill-Def 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC171H282N56O53S6

DescriptionStandard

        LSCLFENQAVSAIACGASCITRKGKRGGWCSNGVCRCTPN
    

Molecular Weight4162.80 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.41

Charge Density (pH 7.0) 0.0925

GRAVY Index0.05

Hydrophobic Moment 0.69

Boman Index0.01

Instability Index50.19

Aliphatic Index 63.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1774.00

LogP -25.37

H-bond Donors 69.0

H-bond Acceptors 63.0

Rotatable Bonds 136.0

Heavy Atoms 286.0

Ring Count 4.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421321 VERIFIED: YES

Provenance & Taxonomy

OrganismHermetia illucens [Animal]

FamilyDefensin

Tax ID343691

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans B59630

Activity32 μM

MethodIC50

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