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MYP_065179
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Basic Information
Beta-defensin 103 (Beta-defensin 3) (BD-3) (DEFB-3) (HBD3) (hBD-3) (Defensin; beta 103) (Defensin-like protein)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
67 amino acids
C344H568N104O82S7
Standard
Sequence
MRIHYLLFALLFLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
Physicochemical Analysis
7697.29 Da
10.15
11.61
11.19
0.1733
0.00
0.63
-0.05
55.16
95.97
0.0896
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3011.71
-23.80
115.0
103.0
259.0
537.0
11.0
69.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0146179 VERIFIED: NO
Provenance & Taxonomy
Pongo abelii [Animal]
Defensin
9601
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/H2PPI1/entry
RECORD: Rec_0149057 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20020115602A1/en PatentUS 2002/0115602 A1
RECORD: Rec_0172916 VERIFIED: NO
Provenance & Taxonomy
Piliocolobus tephrosceles [Animal]
Defensin
591936
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8C9LY41/entry
RECORD: Rec_0212010 VERIFIED: NO
Provenance & Taxonomy
Cercocebus atys [Bacterium]
Defensin
9531
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A2K5NC17/entry
RECORD: Rec_0220665 VERIFIED: NO
Provenance & Taxonomy
Colobus angolensis palliatus [Bacterium]
Defensin
336983
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A2K5K965/entry
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