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MYP_065176
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Basic Information
Pleurocidin analogue from Pleuronectes americanus
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C141H221N51O29
Standard
Sequence
RWRSFFKKAAHRGKHVGKRARTHYL
Physicochemical Analysis
3094.59 Da
12.00
9.02
8.65
0.3607
-1.33
0.59
-0.47
57.71
39.20
0.1600
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1337.82
-11.68
52.0
41.0
104.0
221.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010094 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
5.0
PaperSung W. S., Lee D. G.. Pleurocidin- derived antifungal peptides with selective membrane-disruption effect. Bioche. Biophys. Res. Commun., 2008, 369, 858-861.
RECORD: Rec_0141837 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028
2.5-5 μM
MIC
PMID18325325 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18325325/
RECORD: Rec_0151677 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Trichosporon beigelii KCTC 7707
2.5 μM
MIC
PMID18325325 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18325325/
RECORD: Rec_0236109 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18325325/ PMID18325325 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18325325/
RECORD: Rec_0317006 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
5.0
PaperSung W. S., Lee D. G.. Pleurocidin- derived antifungal peptides with selective membrane-disruption effect. Bioche. Biophys. Res. Commun., 2008, 369, 858-861.
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