Peptide Database

Peptide NameP11

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC157H247N45O34S

DescriptionStandard

        PPIPIPDPPQRNRPPPRWFISLMVIRIH
    

Molecular Weight3340.99 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.05

Net Charge (pH 7.4) 2.94

Charge Density (pH 7.0) 0.1088

GRAVY Index-0.45

Hydrophobic Moment 0.59

Boman Index-0.02

Instability Index72.74

Aliphatic Index 93.93

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1200.49

LogP -5.76

H-bond Donors 39.0

H-bond Acceptors 39.0

Rotatable Bonds 93.0

Heavy Atoms 237.0

Ring Count 13.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149436 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Replication inhibitor

TargetRabies virus (Phosphoprotein); BSR

MethodGFP assay

PaperAntiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides. | Real E, Rain JC, Battaglia V, Jallet C, Perrin P, Tordo N, Chrisment P, D'Alayer J, Legrain P, Jacob Y. | J Virol. 2004 | PMID:15220414 PMID15220414 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15220414/