Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length203 amino acids

Chemical FormulaC1044H1602N244O305S7

DescriptionStandard

        MLYLAFSEYFFQTSSFAYYTAGAFNKTIAEETYSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATETPLISLQPDSFTLEIQGSMEVFAVLPDSTTQSLFTMNITANTSIALNIFNQKLMGSLCLNRLQFSLTHSNVGFFEVSLLENILSYILQTEVIPSANAKLSKGFPLPNLANVTLTRPHITIVQGYVLISTDVHYNH
    

Molecular Weight22675.79 Da

Isoelectric Point (pI)5.06

Net Charge (pH 7.0)-6.14

Net Charge (pH 7.4) -6.62

Charge Density (pH 7.0) -0.0303

GRAVY Index0.30

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index45.82

Aliphatic Index 100.39

Aromaticity 0.1281

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16390.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0317001 VERIFIED: NO

Provenance & Taxonomy

OrganismCairina moschata domestica (Muscovy Duck (domestic type)) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria