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MYP_065111
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Basic Information
CPF-13 (Variant of CPF-C1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C91H152N24O19
Standard
Sequence
GFGSLLGKALRLWKKVL
Physicochemical Analysis
1886.33 Da
11.26
3.76
3.55
0.2210
0.51
0.75
0.19
24.68
137.65
0.1176
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
704.90
-2.44
26.0
23.0
65.0
134.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0299542 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Introduction of D-amino acid(s). (Look at 'Stereochemistry')
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Gram-positive:Staphylococcus aureus ATCC 25923
64 μg/mL
MIC
PMID32590058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32590058/
RECORD: Rec_0308280 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Introduction of D-amino acid(s). (Look at 'Stereochemistry')
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Gram-positive:Staphylococcus aureus ATCC 25923
8 μg/mL
MIC
PMID32590058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32590058/
RECORD: Rec_0321894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Introduction of D-amino acid(s). (Look at 'Stereochemistry')
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
mouse RBCs
PMID32590058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32590058/
RECORD: Rec_0351424 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PMID32590058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32590058/
RECORD: Rec_0357445 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
MRSA 075 isolated from clinics
8 μg/mL
MIC
PMID32590058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32590058/
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