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MYP_065102
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Basic Information
Temporin L [R11K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C83H121N17O16
Standard
Sequence
FVQWFSKFLGKIL
Physicochemical Analysis
1612.95 Da
10.00
1.76
1.55
0.1352
0.87
0.63
0.42
10.98
112.31
0.3077
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.67
0.61
19.0
18.0
52.0
116.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0266933 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas syringae pv. tabaci 1918NCPPB
24 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0328121 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Saccharomyces cerevisiae
6 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0334055 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
6 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0346397 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
8407.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
6 μM
Hemolysis
PaperMangoni ML, Carotenuto A, Auriemma L, et al. Structure-activity relationship, conformational and biological studies of temporin L analogues. J Med Chem. 2011 Mar 10;54(5):1298-1307. doi:10.1021/jm1012853. PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0356251 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 15692
24 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
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