Peptide Database

Peptide NameOmega-ctenitoxin-Cs1a / CsTx-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC353H577N111O106S9

DescriptionStandard

        SCIPKHEECTNDKHNCCRKGLFKLKCQCSTFDDESGQPTERCACGRPMGHQAIETGLNIFRGLFKGKKKNKKTK
    

Molecular Weight8360.62 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)7.65

Net Charge (pH 7.4) 7.14

Charge Density (pH 7.0) 0.1033

GRAVY Index-1.01

Hydrophobic Moment 0.66

Boman Index-0.29

Instability Index47.87

Aliphatic Index 39.59

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3569.00

LogP -43.32

H-bond Donors 130.0

H-bond Acceptors 126.0

Rotatable Bonds 293.0

Heavy Atoms 579.0

Ring Count 10.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047476 VERIFIED: YES

Provenance & Taxonomy

OrganismCupiennius salei [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetDrosophila melanogaster

Activity0.35

MethodLD50

RECORD: Rec_0048143 VERIFIED: YES

Provenance & Taxonomy

OrganismCupiennius salei [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetEscherichia coli SBS 363

Activity15.63-31.25 μM

MethodMIC

RECORD: Rec_0081276 VERIFIED: YES

Provenance & Taxonomy

OrganismCupiennius salei [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetTrypanosoma brucei brucei MiTat1.2

RECORD: Rec_0265121 VERIFIED: YES

Provenance & Taxonomy

OrganismCupiennius salei [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetEscherichia coli ATCC 25922

RECORD: Rec_0316022 VERIFIED: YES

Provenance & Taxonomy

OrganismCupiennius salei [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetStaphylococcus aureus ATCC 29213

Activity250 μM

MethodMIC