Peptide Database

Peptide NameEsculentin-1N protein (Fragment)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC327H556N92O105S4

DescriptionStandard

        GTISLSLCEQKRDDDEEEGSETKRGIFFKLAGKKIKNLLISGLKNIGKEVGMDVVRTGIDIAGCKIKGEC
    

Molecular Weight7584.73 Da

Isoelectric Point (pI)7.89

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.47

Charge Density (pH 7.0) 0.0107

GRAVY Index-0.35

Hydrophobic Moment 0.63

Boman Index-0.07

Instability Index25.13

Aliphatic Index 93.29

Aromaticity 0.0286

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3235.60

LogP -33.52

H-bond Donors 115.0

H-bond Acceptors 110.0

Rotatable Bonds 277.0

Heavy Atoms 528.0

Ring Count 2.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128182 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

FamilyEsculentin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0231252 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Tax ID8409

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal