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MYP_065027
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Basic Information
Hybrid (Derived from Melittin and thanatin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
36 amino acids
C188H323N61O45S3
Standard
Sequence
GLPLLISWIKRKRQQGSKKPVPIIYCNRRTGKCQRM
Physicochemical Analysis
4254.15 Da
11.50
9.73
9.49
0.2704
-0.72
0.54
-0.28
59.23
83.89
0.0556
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1764.12
-15.96
65.0
58.0
146.0
297.0
6.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021862 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
sheep blood cells
PMID30701481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30701481/
RECORD: Rec_0121633 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID30701481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30701481/
RECORD: Rec_0134824 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli JM 109
0.6-1.2 μM
MIC
PMID30701481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30701481/
RECORD: Rec_0187908 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Staphylococcus aureus
0.9-1.5 μM
MIC
PMID30701481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30701481/
RECORD: Rec_0197186 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID30701481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30701481/
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