Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC754H1175N213O218S7

DescriptionStandard

        MSKVQFKQRAVTEAIFVHCSATKATMNVGLREIRQWHKEQGWLDVGYHFIIRRDGTIEEGRPVGVVGSHVKDWNSKSVGVCLVGGIDDKGKYEANFTPAQMHSLKEKLADLLDMYPDAEVKAHHDVAPKACPSFNLSRWLKTGELVTSDWG
    

Molecular Weight16936.15 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.44

Charge Density (pH 7.0) 0.0073

GRAVY Index-0.39

Hydrophobic Moment 0.75

Boman Index-0.01

Instability Index43.22

Aliphatic Index 77.42

Aromaticity 0.0861

Extinction Coeff. Reduced 31970.00

Extinction Coeff. Oxidized 32095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6916.52

LogP -64.63

H-bond Donors 243.0

H-bond Acceptors 233.0

Rotatable Bonds 564.0

Heavy Atoms 1192.0

Ring Count 30.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352398 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage P694 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic