Peptide Database

Peptide NameyczN signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Alkaline protease secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC159H246N34O42S

DescriptionStandard

        MSGYSNGGGYGGISSFALIVVLFILLIIVGTAF
    

Molecular Weight3337.92 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0152

GRAVY Index1.56

Hydrophobic Moment 0.22

Boman Index0.67

Instability Index20.77

Aliphatic Index 138.79

Aromaticity 0.1515

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1179.22

LogP -7.64

H-bond Donors 42.0

H-bond Acceptors 43.0

Rotatable Bonds 106.0

Heavy Atoms 236.0

Ring Count 5.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390960 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis subsp. subtilis str. 168 [Bacterium]

FamilyTat signal peptide

Tax ID224308

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Alkalineprotease (alk) secretion

TargetBacillus amyloliquefaciens 111018

Activity12448.2 U/mL

MethodProtease activity assay

PaperLiu Y, Shi C, Li D, et al. Engineering a highly efficient expression system to produce BcaPRO protease in Bacillus subtilis by an optimized promoter and signal peptide[J]. International journal of biological macromolecules, 2019, 138: 903-911. PMID31356949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31356949/