Peptide Database

Peptide NameLaR2C

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral assembly inhibition ▸ Assembly inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC140H220N34O41

DescriptionStandard

        KYKETDLLILFKDDYFAKKNEERK
    

Molecular Weight3035.45 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.54

Charge Density (pH 7.0) 0.0318

GRAVY Index-1.35

Hydrophobic Moment 0.25

Boman Index-0.38

Instability Index24.93

Aliphatic Index 69.17

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1278.22

LogP -7.55

H-bond Donors 44.0

H-bond Acceptors 42.0

Rotatable Bonds 109.0

Heavy Atoms 215.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066934 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyHost-derived peptide

Tax ID9606;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Replication inhibitor Assembly inhibitor

TargetHepatitis C virus (Translation); Huh7

Activity80-95 %

MethodFilter binding assay

PaperA peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation. | Pudi R, Ramamurthy SS, Das S. | J Virol. 2005 | PMID:16014945 PMID16014945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16014945/

RECORD: Rec_0180927 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0422919 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 8.3%, T 41.7%, C 50.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial