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MYP_064963
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Basic Information
HEXIM1 (147-164), BR
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C104H180N42O21
Standard
Sequence
QLGKKKHRRRPSKKKRHW
Physicochemical Analysis
2354.81 Da
12.00
9.93
9.62
0.5516
-2.84
0.40
-1.03
116.98
21.67
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1089.42
-10.44
41.0
33.0
86.0
167.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0151612 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human breast adenocarcinoma MDA-MB-231[0-10% Killing = 100 microM]
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0166934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 26734838 PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0168585 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis
128 μM
MIC
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0173387 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis VR
128 μM
MBC
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0197617 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
128 μM
MIC
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
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