Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC423H675N123O120S8

DescriptionStandard

        LKFLYLCYLSLLFSASRSGKSCWFLKGHCKQNCKPSEQVKKPCKNGDYCCMPSKTESQPHRSLQAPTKKTQTFNNGLRENIRNL
    

Molecular Weight9660.16 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)10.86

Net Charge (pH 7.4) 10.43

Charge Density (pH 7.0) 0.1293

GRAVY Index-0.75

Hydrophobic Moment 0.68

Boman Index-0.18

Instability Index63.45

Aliphatic Index 56.90

Aromaticity 0.0952

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3988.51

LogP -44.80

H-bond Donors 144.0

H-bond Acceptors 141.0

Rotatable Bonds 326.0

Heavy Atoms 674.0

Ring Count 16.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160798 VERIFIED: NO

Provenance & Taxonomy

OrganismOtolemur garnettii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence