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MYP_064873
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Basic Information
[Arg]7 -VmCT1
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C74H112N18O15
Standard
Sequence
FLGALWRVAKSVF
Physicochemical Analysis
1493.79 Da
11.00
1.76
1.55
0.1353
1.13
0.60
0.38
20.92
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
536.46
-1.11
20.0
17.0
46.0
107.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0154860 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0163502 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human RBCs [Hemolysis observed in the range 0.1 –100 micromol/L
100
Hemolysis
PMID33442883;31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33442883/
RECORD: Rec_0223002 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli SBS 363 (MIC=1.6 μmol/L)，Serratia marcescens ATCC 4112
0.2 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0270628 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida tropicalis IOC 4560
0.8 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0355272 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Antiparasitic Antiprotozoal
MCF-7
18.0±2.7
IC50
PMID33442883;31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33442883/
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