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MYP_064869
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Basic Information
Pore-forming peptide ameobapore B (Parasite, amoebozoa, protozoa, protists)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Standard
77 amino acids
C366H604N96O110S6
Standard
Sequence
GAILCNLCKDTVKLVENLLTVDGAQAVRQYIDNLCGKASGFLGTLCEKILSFGVDELVKLIENHVDPVVVCEKIHAC
Physicochemical Analysis
8301.68 Da
5.14
-3.11
-3.53
-0.0404
0.48
0.66
0.18
14.54
125.19
0.0390
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3294.43
-28.23
116.0
115.0
282.0
578.0
6.0
82.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0087611 VERIFIED: YES
Provenance & Taxonomy
Entamoeba histolytica [Protist]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
5-77; 8-71; 35-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
Gram-positive bacterium: Micrococcus luteus
5 μM
MIC
PMID7715451 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7715451/
RECORD: Rec_0089214 VERIFIED: YES
Provenance & Taxonomy
Entamoeba histolytica [Protist]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
5-77; 8-71; 35-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
PMID7715451 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7715451/
RECORD: Rec_0149358 VERIFIED: NO
Provenance & Taxonomy
Entamoeba histolytica [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0204282 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0214006 VERIFIED: YES
Provenance & Taxonomy
Entamoeba histolytica [Protist]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperAmoebapores, a family of membranolytic peptides from cytoplasmic granules of Entamoeba histolytica: isolation, primary structure, and pore formation in bacterial cytoplasmic membranes.
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