Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC836H1383N243O246S6

DescriptionStandard

        MKTQRDGPSLGRWSLVLLLLGLTMPLAITAQVLSYQEAVLRAVDGLNQRSLDANLYRLLNLDPRPTLDGDPDTPKPVSFTVKETVCPRTIQRSPEECDFKKDGLVKRCVGTVILNQARDSFDISCDKDERKVARLGGFLQKAREKIARGFKKIGQKINDFLGKLAPRTEA
    

Molecular Weight18966.79 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)7.48

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.0440

GRAVY Index-0.37

Hydrophobic Moment 0.90

Boman Index-0.11

Instability Index34.79

Aliphatic Index 94.06

Aromaticity 0.0529

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7949.96

LogP -86.71

H-bond Donors 279.0

H-bond Acceptors 260.0

Rotatable Bonds 645.0

Heavy Atoms 1331.0

Ring Count 20.0

Amide Bonds 182.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078901 VERIFIED: YES

Provenance & Taxonomy

OrganismCebus capucinus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetEscherichia coli

RECORD: Rec_0210131 VERIFIED: YES