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MYP_064816
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Basic Information
Unnamed
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C23H27N3O6
Standard
Sequence
YPY
Physicochemical Analysis
441.48 Da
5.52
-0.24
-0.45
-0.0806
-1.40
0.01
0.21
47.80
0.00
0.6667
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
153.19
0.77
5.0
6.0
8.0
32.0
3.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0134904 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory DPP-IV inhibitory
Dipeptidyl peptidase IV
243.7±2.8 μM
IC50
RECORD: Rec_0168030 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
243.7
IC50
PaperNongonierma A. B., FitzGerald R. J.. Susceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis. Food Chemistry 145, 845-852, 2014.
RECORD: Rec_0179937 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
243.7 μM
IC50
PaperSusceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis | Nongonierma, A. et al. | DOI: 10.1016/j.foodchem.2013.08.097 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0351537 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-glucosidase inhibitory
Alpha-glucosidase
25800.0
IC50
PaperMatsui T., Oki T., Osajima Y.. Isolation and identification of peptidic alpha-glucosidase inhibitors derived from sardine muscle hydrolyzate. Z Naturforsch C 54:259-263 (1999).