Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC543H880N152O163S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRMHVTAVELPSASISLLPGSGIKLVIGNASLTINMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNSGPTSISLTSCRTTSGDIDIKLNGKR
    

Molecular Weight12273.98 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)5.21

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0457

GRAVY Index-0.02

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index27.62

Aliphatic Index 93.16

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5043.53

LogP -57.92

H-bond Donors 180.0

H-bond Acceptors 175.0

Rotatable Bonds 407.0

Heavy Atoms 862.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043480 VERIFIED: NO

Provenance & Taxonomy

OrganismGrantiella picta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria