Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC440H711N137O117S9

DescriptionStandard

        MKLLFLSLAILLAMEPVMPGECWLHGHCRLVCRDGEDHVIRCHNRKRCCVPDHYLTIQPVTIDGQLDWTTPHVTKKGKKHNKNRNRG
    

Molecular Weight10080.79 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)6.06

Net Charge (pH 7.4) 5.38

Charge Density (pH 7.0) 0.0696

GRAVY Index-0.46

Hydrophobic Moment 0.61

Boman Index-0.10

Instability Index49.51

Aliphatic Index 85.06

Aromaticity 0.0460

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4068.30

LogP -36.09

H-bond Donors 147.0

H-bond Acceptors 139.0

Rotatable Bonds 334.0

Heavy Atoms 703.0

Ring Count 18.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077806 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence