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MYP_064630
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Basic Information
Ocellatin-PT8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
32 amino acids
C146H251N43O42S
Standard
Sequence
GVFDIIKGAGKQLIARAMGKIAEKVGLNKDGN
Physicochemical Analysis
3312.88 Da
9.82
2.76
2.55
0.0863
-0.05
0.74
0.06
4.45
103.75
0.0312
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1398.59
-13.38
47.0
46.0
120.0
232.0
1.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084347 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
60 μM
MIC
RECORD: Rec_0183836 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
Klebsiella pneumoniae ATCC 700603
240 μM
MIC
PaperCharacterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus
RECORD: Rec_0192763 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Klebsiella pneumoniae ATCC 700603
800 μg/mL
MIC
PMID26107622;27463422 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0240580 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pustulatus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Escherichia coli ATCC 25922
200 μg/mL
MIC
PMID26107622;27463422 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26107622/
RECORD: Rec_0243437 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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