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MYP_064603
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Basic Information
Antimicrobial peptide Polydim-I
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C117H193N27O27S
Standard
Sequence
AVAGEKLWLLPHLLKMLLTPTP
Physicochemical Analysis
2442.01 Da
8.64
0.88
0.64
0.0402
0.65
0.45
0.35
38.35
146.36
0.0455
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
822.32
-0.93
27.0
30.0
75.0
172.0
6.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013533 VERIFIED: NO
Provenance & Taxonomy
Polybia dimorpha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
M. abscessus
RECORD: Rec_0014722 VERIFIED: YES
Provenance & Taxonomy
Polybia dimorpha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii Isolate AB 02
25 μM
MIC
PMID30974767;28570651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30974767/
RECORD: Rec_0037490 VERIFIED: YES
Provenance & Taxonomy
Polybia dimorpha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive Anti-Gram-negative
A. calcoaceticcus
84 μg/mL
MIC
PMID30974767;28570651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30974767/
RECORD: Rec_0104069 VERIFIED: YES
Provenance & Taxonomy
Polybia dimorpha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
M. abscessus subsp. massiliense
60.8 μg/mL
MIC
PaperAntimycobacterial Activity of a New Peptide Polydim-I Isolated from Neotropical Social Wasp Polybia dimorpha
RECORD: Rec_0131087 VERIFIED: YES
Provenance & Taxonomy
Polybia dimorpha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii Isolate AB 72
25 μM
MIC
PMID30974767;28570651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30974767/
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