Peptide Database

Peptide NameNF-kappa-B essential modulator

Function Ontology

Antiviral

Standard StatusStandard

Sequence Length419 amino acids

Chemical FormulaC2063H3381N621O661S23

DescriptionStandard

        MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
    

Molecular Weight48197.18 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-11.59

Net Charge (pH 7.4) -12.64

Charge Density (pH 7.0) -0.0277

GRAVY Index-0.86

Hydrophobic Moment 0.79

Boman Index-0.23

Instability Index70.93

Aliphatic Index 77.85

Aromaticity 0.0310

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 15065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020488 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNF-kB regulator

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser31, Ser43, Ser68, Ser85, Ser376, Ser387

Bio-Activity Profile

Function

Antiviral RNA-sensing effector