‹ ›
MYP_064539
← PREVIOUS NEXT → BACK
Basic Information
Peptide 12
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
17 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIKKFLKSXKKFVKXFK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0132907 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The X (position: 9 and 15) in sequence indicate Aib residues (2-Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID33466998 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33466998/
RECORD: Rec_0141061 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
non-canonical residue code at 9,15; Z)
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis NBRC 12298
1.56 μM
MIC
PMID31667994;35073323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31667994/
RECORD: Rec_0143568 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The X (position: 9 and 15) in sequence indicate Aib residues (2-Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Staphylococcus aureus
12.5 μM
MIC
PMID33466998 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33466998/
RECORD: Rec_0178412 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
selenocysteine at 9,15; U)
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa NBRC13275
3.125 μM
MIC
PMID31667994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31667994/
RECORD: Rec_0180737 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 9,15
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NBRC 13276
12.5 μM
MIC
PMID33466998 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33466998/
FIRST PREV 1 2 3 4 ... 6 NEXT LAST
Showing 5 records on this page · Page 2 of 6