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MYP_064539
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Basic Information
Peptide 12
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
17 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIKKFLKSXKKFVKXFK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009268 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
non-canonical residue code at 9,15; Z)
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Escherichia coli DH5alpha
3.125 μM
MIC
PMID31667994;35073323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31667994/
RECORD: Rec_0061340 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
selenocysteine at 9,15; U)
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Escherichia coli BBRC 3972
3.125 μM
MIC
PMID31667994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31667994/
RECORD: Rec_0064389 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The X (position: 9 and 15) in sequence indicate Aib residues (2-Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
multiple-drug resistant Pseudomonas aeruginosa
3.125 μM
MIC
PMID33466998 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33466998/
RECORD: Rec_0107779 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 9,15
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis NBRC 12298
1.56 μM
MIC
PMID33466998 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33466998/
RECORD: Rec_0108596 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 9,15
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa NBRC 13275
3.125 μM
MIC
PMID33466998 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33466998/
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