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MYP_064527
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Basic Information
Cecropin(1-7)+Melittin(2-9) K7(Me 3 )
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
15 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKLFKXIGAVLKVL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0175093 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Escherichia coli ML-35
50 μM
LD50
PMID11502512;20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11502512/
RECORD: Rec_0200769 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 7
Bio-Activity Profile
Hemolytic
sheep red blood cells
7.8 μM
Hemolysis
PMID11502512;20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11502512/
RECORD: Rec_0226141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania donovani MHOM/S.D./00/1S-2D promastigote
3.7 μM
IC50
PMID11502512;20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11502512/
RECORD: Rec_0230811 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania donovani MHOM/S.D./00/1S-2D promastigote
2.3 μM
LC50
PMID11502512;20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11502512/
RECORD: Rec_0311220 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 7
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania sp. promastigote
32.1 μM
LD50
PMID11502512;20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11502512/
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