Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2412H3813N613O679S16

DescriptionStandard

        MARGPDSTLRWATLVVLASLGTAVTANPNPGVVARITQKGLDYACQQGVTILQKELEKITIPPFSGSFKVKYLGKGQYSFYSMVIRGFKLPSSQIRPSPNQGLDLSIKDASIKISGKWKARKNFIKAKGNFDLSVEGISISAGLKLGYDPASGHSTVACSSCNSHINSVGLHISGSSLGWLIQLFHKKIESSIQNTMNSKVCEVVTSTVSSKLQPYFETLPVTVKLDNVAGIDYSLVAPPKAMADNLDVHLKGEVFSLAHRSPSPFAPPVLNLPTDHDLMVYLGISEYFFNTAGLVYQEAGVLNLTLKDDMIPKESKFHLTTNFFGTLIPQVAKMFPNMQVQLLIWASVPPHLTVCPTGLDIIFVLETQAFAVLPNSSLAPLFLLEMNTNVSVDVGARSDRLVGELKLNKLLLNLKHSDIGPFSVELLQMVMNYVLPTVVLPEINEKLQKGFPLPLPAYIQLFNLVLQPHQDFLLFGADVHFG
    

Molecular Weight52775.81 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)4.52

Net Charge (pH 7.4) 3.52

Charge Density (pH 7.0) 0.0094

GRAVY Index0.17

Hydrophobic Moment 0.65

Boman Index0.17

Instability Index33.97

Aliphatic Index 104.70

Aromaticity 0.0849

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350150 VERIFIED: NO

Provenance & Taxonomy

OrganismCamelus ferus (Wild bactrian camel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria