Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC416H687N119O133S12

DescriptionStandard

        MKSLMLTLASFMLLAQVVSGSWYVRKCANKTGNCRSMCRVGETAIQPATGICPKEKMCCILSGKEFNSAACGENSKTTREAQASEASTTVSY
    

Molecular Weight9868.40 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.0482

GRAVY Index-0.07

Hydrophobic Moment 0.70

Boman Index0.01

Instability Index27.72

Aliphatic Index 64.78

Aromaticity 0.0543

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4089.63

LogP -52.01

H-bond Donors 152.0

H-bond Acceptors 150.0

Rotatable Bonds 334.0

Heavy Atoms 680.0

Ring Count 8.0

Amide Bonds 98.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0370487 VERIFIED: NO

Provenance & Taxonomy

OrganismAiluropoda melanoleuca [Animal]

FamilyDefensin

Tax ID9646

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence