‹ ›
MYP_064504
← PREVIOUS NEXT → BACK
Basic Information
RJ1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C96H184N32O22
Standard
Sequence
KAKAKAKAKAKAKAKAKAKAK
Physicochemical Analysis
2138.69 Da
11.00
10.75
10.53
0.5119
-1.19
0.16
-0.49
9.52
47.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
931.54
-9.29
33.0
33.0
85.0
150.0
0.0
20.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0159745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
RECORD: Rec_0252809 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
herpes simplex virus 2 (HSV-2) | MRC-5 cells
53.2 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperA wide range of medium-sized, highly cationic, alpha-helical peptides show antiviral activity against herpes simplex virus. | Jenssen H, Andersen JH, Mantzilas D, Gutteberg TJ. | Antiviral Res. 2004 Nov;64(2):119-26. | DOI:10.1016/j.antiviral.2004.08.003 | PMID:15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
RECORD: Rec_0327583 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
RECORD: Rec_0362385 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
human fibroblasts(MRC-5 cells)
455 μM
CC50
PaperPubMed PMID: 15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
RECORD: Rec_0417174 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
herpes simplex virus 2(HSV-2):inhibition of HSV-2 infection in MRC-5 cells
53.2 μM
IC50
PaperPubMed PMID: 15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/