Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC439H685N113O116S9

DescriptionStandard

        MKIFFIFLVFVFTVLGHKKSVPEQKIRDDIERKNKCDLVLGVCKPECNSWEYIFNYCDAEPCCVIREYRLRIMSELMQRY
    

Molecular Weight9690.41 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.16

Charge Density (pH 7.0) 0.0193

GRAVY Index-0.07

Hydrophobic Moment 0.66

Boman Index-0.02

Instability Index44.52

Aliphatic Index 90.00

Aromaticity 0.1375

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3721.45

LogP -22.58

H-bond Donors 135.0

H-bond Acceptors 128.0

Rotatable Bonds 325.0

Heavy Atoms 677.0

Ring Count 16.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301165 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence