Peptide Database

Peptide NameUrotensin-2

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Vasoactive neuropeptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC66H90N14O17S2

DescriptionStandard

        GPPSECFWKYCV
    

Molecular Weight1415.63 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-0.26

Net Charge (pH 7.4) -0.50

Charge Density (pH 7.0) -0.0216

GRAVY Index-0.17

Hydrophobic Moment 0.29

Boman Index0.18

Instability Index87.65

Aliphatic Index 24.17

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 485.41

LogP -2.21

H-bond Donors 18.0

H-bond Acceptors 19.0

Rotatable Bonds 38.0

Heavy Atoms 99.0

Ring Count 6.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358032 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

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