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MYP_064335
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C134H230N36O32
Standard
Sequence
GFLGPLLKLGLKGAAKLLPQLLPSRQQ
Physicochemical Analysis
2857.48 Da
11.26
3.76
3.55
0.1392
0.25
0.60
0.17
40.70
137.41
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1083.01
-6.82
35.0
36.0
96.0
202.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0308620 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Methicillin-resistant Staphylococcus aureus
2.5 μM
MIC
PMID22800690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800690/
RECORD: Rec_0309236 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part D 6 (2011) 206-212. Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions
RECORD: Rec_0338197 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal] [Animal]; Xenopus laevis [Animal] [Animal]; Silurana paratropicalis [Animal]
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-negative
Escherichia coli
40 μM
MIC
RECORD: Rec_0359366 VERIFIED: YES
Provenance & Taxonomy
Silurana paratropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
50 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0401935 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
40 μM
MIC
PMID22800690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800690/
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